Name | Nipecotic acid |
Synonyms | Nipecotic acid L-NIPECOTIC ACID DL-Nipecotic acid DL-NIPECOTIC ACID D(-)-NIPECOTIC ACID (-)-D-NIPECOTIC ACID 3-Piperidinecarboxylic acid Piperidin-3-carboxylic acid 3-PIPERIDINECARBOXYLIC ACID piperidine-3-carboxylic acid DL-3-PIPERIDINECARBOXYLIC ACID (3R)-(-)-PIPERIDIN-3-YLCARBOXYLIC ACID |
CAS | 498-95-3 262853-93-0 |
EINECS | 207-873-9 |
InChI | InChI=1/C6H11NO2/c8-6(9)5-2-1-3-7-4-5/h5,7H,1-4H2,(H,8,9) |
Molecular Formula | C6H11NO2 |
Molar Mass | 129.16 |
Density | 1.1426 (rough estimate) |
Melting Point | 261 °C (dec.) (lit.) |
Boling Point | 239.22°C (rough estimate) |
Flash Point | 114.5°C |
Water Solubility | Soluble in water |
Solubility | water: soluble50mg/mL, clear, colorless to faintly yellow |
Vapor Presure | 0.0026mmHg at 25°C |
Appearance | White-like powder |
Color | White |
Merck | 14,6560 |
BRN | 81096 |
pKa | pK1:3.35(+1);pK2:10.64(0) (25°C) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | 1.4587 (estimate) |
MDL | MFCD00005992 |
Physical and Chemical Properties | Off-white to white crystals. |
Use | For Organic synthesis |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
WGK Germany | 3 |
RTECS | TM6125380 |
HS Code | 29339900 |
Hazard Class | IRRITANT |
White Crystal or crystalline powder, odorless or slightly bad smell, slightly sour. Easily soluble and ethanol, room temperature 100mL water can dissolve 1. 6G, insoluble in ether and Ester solvents. The pH of the 1% aqueous solution was 3.0 to 4.0. It is stable to heat, acid and alkali.
nicotinic acid naturally exists in the grain germ, peanut meat, industrial can be 3 A methyl pyridine as raw material, with potassium permanganate or gas phase and ammonia oxidation. It is also possible to use 2-methyl -5-ethyl pyridine as a raw material, which is oxidized and decarboxylated to form nicotinic acid.
niacin is an important hydrogen transmitter in body tissues and an anti-dermatosis factor. It can maintain the health of skin and nerves and promote digestion. It can also be used as a beverage additive and a color aid for meat products. China's provisions can be used to strengthen cereals and their products, the use of 40~50mg/kg; In the fortified infant food use of 30~40mg/kg; the amount used is 10-40mg/kg in the drink and milk drink.
use | for organic synthesis |